NetAffx: Affymetrix probesets and annotations

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NetAffx: Affymetrix probesets and annotations

NetAffx (http://www.affymetrix.com) details and annotates probesets on Affymetrix GeneChip microarrays. These annotations include (i) static information specific to the probeset composition; (ii) sequence annotations extracted from public databases; and (iii) protein sequence-level annotations derived from public domain programs, as well as libraries of hidden Markov models (HMMs) developed at ...

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ADAPT: a database of affymetrix probesets and transcripts

UNLABELLED ADAPT is an online database providing comprehensive mappings between Affymetrix probes and RefSeq and Ensembl transcripts. ADAPT was designed to help interpret microarray experiments by providing a means to explore the many-to-many relationships that exist between probes, probesets, transcripts and genes. AVAILABILITY ADAPT can be queried via the web at http://bioinformatics.picr.m...

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Careful analysis of microarray probe design should be an obligatory component of MicroArray Quality Control (MACQ) project [Patterson et al., 2006; Shi et al., 2006] initiated by the FDA (USA) in order to provide quality control tools to researchers of gene expression profiles and to translate the microarray technology from bench to bedside. The identification and filtering of unreliable probes...

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Effects of Multiple Probesets in Affymetrix GeneChips on Identifying Differentially Expressed Genes in iPS Cells

There are multiple probesets that correspond to a gene in Affymetrix GeneChip platform. Different combination and annotation methods will lead to different results of expression when we transform the information from probesets to genes. In this work, we collected seven methods to interpret the multiple probesets for representing a gene. We compared these methods and identified their effects on ...

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A sequence-based identification of the genes detected by probesets on the Affymetrix U133 plus 2.0 array

One of the biggest problems facing microarray experiments is the difficulty of translating results into other microarray formats or comparing microarray results to other biochemical methods. We believe that this is largely the result of poor gene identification. We re-identified the probesets on the Affymetrix U133 plus 2.0 GeneChip array. This identification was based on the sequence of the pr...

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ژورنال

عنوان ژورنال: Nucleic Acids Research

سال: 2003

ISSN: 1362-4962

DOI: 10.1093/nar/gkg121